Description

2-Amino-2-(4-Chlorophenyl)Acetonitrile Hydrochloride is a high-purity, versatile chemical intermediate essential for advanced organic synthesis. Its primary value lies in its role as a key building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is critically needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with specific biological activities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the chlorophenyl moiety for biological activity.
• Fine Chemical Production: Serves as a key starting material for the manufacture of complex dyes, pigments, and other high-value specialty chemicals.
• Research & Development: Employed in academic and industrial R&D labs for method development and the creation of new chemical entities for screening.
• Peptidomimetic Chemistry: The amino nitrile structure makes it valuable for synthesizing peptide analogs and other bio-inspired molecules.

Basic Information

Product Name	2-Amino-2-(4-Chlorophenyl)Acetonitrile Hydrochloride
CAS No.	49704-71-4
Molecular Formula	C8H8ClN2•HCl
Molecular Weight	205.07 g/mol (Free base: 168.62 g/mol)
Synonyms	(4-Chlorophenyl)glycinonitrile hydrochloride; 2-Amino-2-(4-chlorophenyl)ethanenitrile hydrochloride; 4-Chloro-α-aminobenzeneacetonitrile hydrochloride; p-Chlorophenylglycinonitrile hydrochloride; α-Amino-p-chlorophenylacetonitrile hydrochloride; Amino(4-chlorophenyl)acetonitrile hydrochloride; 4-Chlorobenzyl cyanide amine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(4-Chlorophenyl)Acetonitrile Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure it meets the highest standards of purity and consistency required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can compromise product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.