Description

3-Amino-5-Iodobenzonitrile is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a nitrile group on an iodinated benzene ring, makes it a valuable precursor for constructing complex molecules. This intermediate is particularly essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the iodine atom for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Building block for organic electronic materials, such as non-linear optical (NLO) chromophores and charge-transport molecules.
• Dye and Pigment Intermediate: Used in the synthesis of specialized azo dyes and high-performance pigments.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories exploring new chemical entities and reaction pathways.

Basic Information

Product Name	3-Amino-5-Iodobenzonitrile
CAS No.	49674-31-9
Molecular Formula	C7H5IN2
Molecular Weight	244.03 g/mol
Synonyms	5-Iodo-3-aminobenzonitrile; 3-Amino-5-iodobenzene carbonitrile; 3-Cyano-5-iodoaniline; Benzonitrile, 3-amino-5-iodo-; 5-Iodo-3-cyanoaniline; 3-Amino-5-iodophenyl cyanide; AIBN (context-specific abbreviation)
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Iodobenzonitrile is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production standards. Custom purity grades, including pharmaceutical intermediates grade, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.