Description

3-Iodo-5-Nitrobenzonitrile is a halogenated aromatic nitrile compound that serves as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both an electron-withdrawing nitro group and a reactive iodine substituent, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and the development of novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of compounds with potential biological activity.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom is an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form new carbon-carbon bonds.
• Ligand and Catalyst Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a starting material for synthesizing molecular probes and tags used in biochemical and diagnostic research.

Basic Information

Product Name	3-Iodo-5-Nitrobenzonitrile
CAS No.	49674-30-8
Molecular Formula	C7H3IN2O2
Molecular Weight	273.01 g/mol
Synonyms	5-Nitro-3-iodobenzonitrile; 3-Iodo-5-nitrobenzenecarbonitrile; Benzonitrile, 3-iodo-5-nitro-; 3-Iodo-5-nitro-benzonitrile; 3-Iodo-5-nitrobenzonitrile; 3-Iodo-5-nitro-benzonitrile; 3-Iodo-5-nitrobenzonitrile (CAS 49674-30-8)
EINECS	Contact for details

Quality Control

Our 3-Iodo-5-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.