Description

5-Amino-3-Bromobenzonitrile is a high-purity aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and a bromo substituent on the benzonitrile core, makes it a versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen and amino groups for structural diversification.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, dyes, and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling reactions to form complex biaryl and amine structures.
• Chemical Biology & Proteomics: Utilized as a building block for designing molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a core component in the synthesis of electron-transport materials and emissive layer dopants.

Basic Information

Item	Details
Product Name	5-Amino-3-Bromobenzonitrile
CAS No.	49674-16-0
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	3-Bromo-5-aminobenzonitrile; 3-Bromo-5-cyanobenzenamine; 5-Amino-3-bromobenzene carbonitrile; Benzonitrile, 5-amino-3-bromo-; 3-Bromo-5-aminophenyl cyanide; 5-Cyano-3-bromoaniline; 3-Bromo-5-cyanoaniline
EINECS	Contact for details

Quality Control

Our 5-Amino-3-Bromobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with major regulatory frameworks including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	145 - 150 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.