Description

1-(2-Aminoethyl)-2-Methyl-5-Nitroimidazole Dihydrochloride Monohydrate is a high-purity, chemically defined nitroimidazole derivative, primarily utilized as a critical pharmaceutical intermediate. Its value lies in its role as a key building block for the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in the development of antimicrobial and antiprotozoal agents. This compound is essential for research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development and production of specialized therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nitroimidazole-based APIs, including antimicrobial and antiparasitic drugs.
• Antiprotozoal Drug Research: Serves as a core scaffold in the development of new treatments for infections caused by protozoa such as Giardia and Trichomonas.
• Antibacterial Agent Synthesis: Used in the research and manufacturing of compounds targeting anaerobic bacterial infections.
• Chemical Reference Standard: Employed as a high-purity standard in analytical laboratories for quality control and method validation.
• Biochemical Research: Utilized in life science research to study enzyme inhibition and cellular mechanisms related to nitroimidazole activity.
• Veterinary Pharmaceutical Development: Applied in the formulation of medicinal products for animal health.

Basic Information

Product Name	1-(2-Aminoethyl)-2-Methyl-5-Nitroimidazole Dihydrochloride Monohydrate
CAS No.	49575-10-2
Molecular Formula	C6H11N5O2 • 2HCl • H2O
Molecular Weight	284.11 g/mol (monohydrate salt form)
Synonyms	2-Methyl-5-nitro-1H-imidazole-1-ethanamine dihydrochloride monohydrate; 1-(2-Aminoethyl)-2-methyl-5-nitroimidazole HCl salt; 2-Methyl-5-nitroimidazole-1-ethylamine dihydrochloride hydrate; NSC 113792; 5-Nitro-1-(2-aminoethyl)-2-methylimidazole dihydrochloride; 1-(2-Aminoethyl)-2-methyl-5-nitro-1H-imidazole dihydrochloride monohydrate
EINECS	Contact for details

Quality Control

Our 1-(2-Aminoethyl)-2-Methyl-5-Nitroimidazole Dihydrochloride Monohydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure compliance with stringent specifications suitable for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	5.0% - 7.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.