Description

Tosactide CAS NO 47931-80-6 is a synthetic peptide derivative of adrenocorticotropic hormone (ACTH). This compound is significant for its role in diagnostic and research applications related to adrenal cortex function. It is primarily utilized by pharmaceutical manufacturers, clinical diagnostic laboratories, and research institutions engaged in endocrinology and metabolic studies.

Application

• Diagnostic Agent: Used in clinical tests to assess adrenal gland function and reserve capacity.
• Pharmaceutical Intermediates: Serves as a key intermediate in the synthesis of specialized peptide-based therapeutics.
• Biochemical Research: A critical tool for studying the structure-activity relationships of ACTH and related peptides in laboratory settings.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method validation and calibration.
• Endocrine Studies: Facilitates research into cortisol production regulation and disorders of the hypothalamic-pituitary-adrenal (HPA) axis.

Basic Information

Product Name	Tosactide
CAS No.	47931-80-6
Molecular Formula	C₉₈H₁₄₀N₂₈O₃₁S
Molecular Weight	2334.4 g/mol
Synonyms	Tosactide; Cosyntropin; Tetracosactide; Tetracosactrin; Synacthen; Cortrosyn; α1-24-Corticotropin; Adrenocorticotropic Hormone Fragment 1-24; ACTH (1-24); Nα-tosyl-ACTH (1-24)
EINECS	Contact for details

Quality Control

Our Tosactide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, peptide content determination, and identity confirmation via mass spectrometry. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and pharmaceutical-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term stability, consider storage at -20°C under desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.