Description

Vasoactive Intestinal Peptide (22-28) CAS NO 47900-24-3 is a specific bioactive fragment of the full-length Vasoactive Intestinal Peptide (VIP), a neuropeptide with significant physiological roles. This heptapeptide sequence retains key biological activity and is a critical research tool for studying receptor interactions and signal transduction pathways. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on neuroscience, immunology, and drug discovery.

Application

• Neuroscientific Research: Used as a reference standard and active agent in studies of VIP receptor (VPAC1/VPAC2) binding, function, and localization in the central and peripheral nervous systems.
• Immunology & Inflammation Studies: Investigated for its modulatory effects on immune cells, cytokine release, and inflammatory responses due to VIP's known anti-inflammatory properties.
• Drug Discovery & Development: Serves as a key pharmacophore for designing and screening novel peptide-based therapeutics targeting GPCRs related to VIP pathways.
• Biochemical Assay Development: Employed in the development and validation of competitive binding assays (e.g., ELISA, RIA) and functional cellular assays.
• Cell Culture & Physiology: Applied in vitro to study its effects on cellular processes such as vasodilation, secretion, and cell proliferation.
• Academic & Educational Use: A standard reagent for graduate and post-graduate level research in biochemistry, pharmacology, and molecular biology.

Basic Information

Product Name	Vasoactive Intestinal Peptide (22-28)
CAS No.	47900-24-3
Molecular Formula	C38H58N10O10
Molecular Weight	814.93 g/mol
Synonyms	VIP (22-28); VIP Fragment 22-28; H-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-NH2; Lys-Lys-Tyr-Leu-Asn-Ser-Ile-amide; Vasoactive Intestinal Polypeptide (22-28); L-Lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-asparaginyl-L-seryl-L-isoleucinamide
EINECS	Contact for details

Quality Control

Our Vasoactive Intestinal Peptide (22-28) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided, reporting results from HPLC for purity, Mass Spectrometry (MS) for identity confirmation, and Amino Acid Analysis (AAA). We support research and development requiring high-purity peptide standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.