Description

4-Cbz-Amino-2-Boc-Amino-Butyric Acid is a high-purity, dual-protected amino acid derivative essential for advanced peptide synthesis. This compound serves as a critical building block, enabling the precise and sequential assembly of complex peptide chains in solid-phase and solution-phase methodologies. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and bioactive compounds.

Application

• Peptide Synthesis: A key protected intermediate for the controlled incorporation of specific amino acid sequences.
• Pharmaceutical Research: Building block for the discovery and development of peptide-based drug candidates and APIs.
• Bioconjugation: Used in the preparation of peptide-protein conjugates for diagnostic and therapeutic applications.
• Combinatorial Chemistry: Valuable scaffold in libraries for high-throughput screening of biological activity.
• Academic Research: Fundamental reagent for studying peptide structure, function, and synthesis methodologies.
• Production of Custom Peptides: Essential for CROs and CDMOs manufacturing bespoke peptides for clients.

Basic Information

Product Name	4-Cbz-Amino-2-Boc-Amino-Butyric Acid
CAS No.	47461-65-4
Molecular Formula	C17H24N2O6
Molecular Weight	352.39 g/mol
Synonyms	N2-[(tert-Butoxy)carbonyl]-N4-(benzyloxycarbonyl)-L-2,4-diaminobutanoic Acid; (2S)-2-[(tert-Butoxycarbonyl)amino]-4-[(benzyloxycarbonyl)amino]butanoic Acid; Boc-Dab(Cbz)-OH; Boc-L-Dab(Cbz)-OH; 2-Boc-amino-4-Cbz-amino-butanoic Acid; Fmoc-Dab(Boc)-OH (precursor-related); L-2,4-Diaminobutanoic Acid, N2-Boc, N4-Cbz-
EINECS	Contact for details

Quality Control

Our 4-Cbz-Amino-2-Boc-Amino-Butyric Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Solubility	Soluble in DMF, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.