Description

4-[2-(Pyrrolidin-1-Yl)Ethoxy]Benzonitrile is a high-purity organic compound featuring a benzonitrile core linked to a pyrrolidine moiety via an ethoxy spacer. This molecular architecture makes it a valuable chemical intermediate and building block for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry, where it serves as a key precursor for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and material science.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API (Active Pharmaceutical Ingredient) synthesis projects.
• Academic and Institutional Research: Used in university and institutional labs for fundamental organic chemistry and medicinal chemistry studies.

Basic Information

Product Name	4-[2-(Pyrrolidin-1-Yl)Ethoxy]Benzonitrile
CAS No.	46745-39-5
Molecular Formula	C13H16N2O
Molecular Weight	216.28 g/mol
Synonyms	4-(2-Pyrrolidin-1-ylethoxy)benzonitrile; 1-[2-(4-Cyanophenoxy)ethyl]pyrrolidine; Benzonitrile, 4-[2-(1-pyrrolidinyl)ethoxy]-; Pyrrolidine, 1-[2-(4-cyanophenoxy)ethyl]-; 4-(2-(Pyrrolidin-1-yl)ethoxy)benzonitrile; 46745-39-5 (CAS); 4-(2-Pyrrolidinoethoxy)benzonitrile
EINECS	Contact for details

Quality Control

Our 4-[2-(Pyrrolidin-1-Yl)Ethoxy]Benzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.