Description

Secretin (21-27) is a bioactive heptapeptide fragment derived from the gastrointestinal hormone secretin. This specific sequence is critical for research into receptor binding and signal transduction mechanisms. It is primarily utilized by pharmaceutical R&D and academic laboratories for biochemical studies and drug discovery programs. The compound offers a valuable tool for investigating pancreatic and gastrointestinal functions.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of secretin receptor (SCTR) interactions and downstream signaling pathways.
• Drug Discovery: Serves as a key pharmacophore model and starting point for the development of novel peptide-based therapeutics targeting metabolic and digestive disorders.
• Academic Studies: Employed in university and institutional labs for teaching and advanced research in endocrinology and peptide chemistry.
• Diagnostic Development: Potential use in the development of immunoassays and diagnostic kits for conditions related to secretin dysfunction.
• Neuroscience Research: Investigated for its role and effects within the central nervous system (CNS).

Basic Information

Product Name	Secretin (21-27)
CAS No.	45323-83-9
Molecular Formula	C34H55N11O11S
Molecular Weight	826.0 g/mol
Synonyms	Secretin fragment 21-27; H-Val-Asp-Gly-Ser-Phe-Thr-Ser-OH; Secretin (21-27) amide (common derivative); Val-Asp-Gly-Ser-Phe-Thr-Ser; SCT(21-27); Secretin heptapeptide; Gastrointestinal peptide fragment
EINECS	Contact for details

Quality Control

Our Secretin (21-27) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications are available upon request to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content (AAA)	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.