Description

n-[Vinyloxycarbonyl]-L-Serine CAS NO 45014-14-0 is a specialized, high-purity amino acid derivative designed for advanced chemical synthesis. This compound is valued for its unique vinyloxycarbonyl protecting group, which offers selective reactivity and stability under various coupling conditions. It is an essential building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of novel peptides, prodrugs, and other bioactive molecules.

Application

• Peptide Synthesis: Serves as a key protected serine derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediates: Used in the research and production of active pharmaceutical ingredients (APIs) and prodrug candidates.
• Bioconjugation: Acts as a versatile linker or spacer molecule for attaching functional groups to proteins, antibodies, or other biomolecules.
• Chemical Biology Research: Employed in the study of enzyme mechanisms and the development of enzyme inhibitors.
• Material Science: A potential monomer or cross-linking agent for creating functional polymers with tailored properties.

Basic Information

Product Name	n-[Vinyloxycarbonyl]-L-Serine
CAS No.	45014-14-0
Molecular Formula	C6H9NO5
Molecular Weight	175.14 g/mol
Synonyms	L-Serine, N-(vinyloxycarbonyl)-; N-VOC-L-Serine; (2S)-2-[[(Ethenyloxy)carbonyl]amino]-3-hydroxypropanoic acid; N-Carboxyvinyloxy-L-serine; VOC-Ser-OH; Ser(Voc)-OH; N-(Vinyloxycarbonyl)serine; Amino acid derivative VOC-Ser
EINECS	Contact for details

Quality Control

Our n-[Vinyloxycarbonyl]-L-Serine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% L-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.