Description

3-Fluoro-Dl-Norleucine is a fluorinated derivative of the non-proteinogenic amino acid norleucine, where a fluorine atom is introduced at the β-carbon position. This structural modification is of significant interest for its role in medicinal chemistry and biochemical research, particularly in the study of enzyme mechanisms and metabolic pathways. It serves as a valuable building block for pharmaceutical intermediates and as a tool compound in life science research for probing protein function and designing enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those targeting metabolic enzymes.
• Biochemical Research: Acts as a substrate analog or inhibitor in enzymatic studies to investigate amino acid metabolism and transport.
• Proteomics & Peptide Chemistry: Incorporated into synthetic peptides to study the effects of fluorination on peptide structure, stability, and biological activity.
• Metabolic Pathway Analysis: Employed as a tracer or modulator in cellular and microbiological studies to elucidate specific biochemical pathways.
• Agrochemical Research: Potential use in the development of new herbicides or plant growth regulators based on amino acid antimetabolites.

Basic Information

Product Name	3-Fluoro-Dl-Norleucine
CAS No.	43163-96-8
Molecular Formula	C6H12FNO2
Molecular Weight	149.16 g/mol
Synonyms	3-Fluoronorleucine; DL-3-Fluoronorleucine; (±)-3-Fluoronorleucine; 2-Amino-3-fluorohexanoic acid; 3-Fluoro-2-aminohexanoic acid; Norleucine, 3-fluoro-; 3-Fluoro-DL-norleucine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-Dl-Norleucine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.