Description

2,3,4-Trimethoxybenzonitrile is a versatile aromatic nitrile derivative characterized by its trimethoxy substitution pattern. This compound serves as a valuable advanced pharmaceutical intermediate (API) and a key building block in organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting the central nervous system.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers due to its electron-withdrawing nitrile group and methoxy donors.
• Chemical Research & Development: A versatile synthon for exploring novel organic reactions, including cyano group transformations and electrophilic aromatic substitutions.

Basic Information

Product Name	2,3,4-Trimethoxybenzonitrile
CAS No.	43020-38-8
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	Benzonitrile, 2,3,4-trimethoxy-; 2,3,4-Trimethoxybenzenecarbonitrile; 3,4,5-Trimethoxybenzonitrile (common numbering variant); TMB-CN; Trimethoxybenzonitrile
EINECS	Contact for details

Quality Control

Our 2,3,4-Trimethoxybenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, GC, NMR, and other relevant analytical techniques. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.