Description

Quinidine Methiodide is a quaternary ammonium salt derivative of the alkaloid quinidine, widely recognized for its pharmacological research applications. This high-purity compound is essential for studying cardiac ion channel modulation and serves as a critical reference standard in analytical chemistry. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals and diagnostic reagents.

Application

• Pharmacological Research: A key tool for investigating the blockade of cardiac potassium channels (e.g., IKr) and its effects on action potential duration.
• Reference Standard: Used as a certified reference material (CRM) in HPLC and LC-MS methods for the quantification of quinidine and related compounds.
• Biochemical Studies: Employed in in vitro assays to study the structure-activity relationships (SAR) of antiarrhythmic agents.
• Fine Chemical Synthesis: Serves as a specialized intermediate or precursor in the synthesis of more complex quaternary ammonium compounds for research purposes.
• Academic & Educational Use: Utilized in university laboratories for teaching advanced concepts in medicinal chemistry and electrophysiology.

Basic Information

Product Name	Quinidine Methiodide
CAS No.	42982-87-6
Molecular Formula	C21H27IN2O2
Molecular Weight	466.36 g/mol
Synonyms	Quinidine Methyl Iodide; (9S)-6'-Methoxycinchonan-9-ol Methyl Iodide; Cinchonan-9-ol, 6'-methoxy-, (9S)-, methiodide; N-Methylquinidinium Iodide; Quinidine Methoiodide; Quinidine, N-methyl-, iodide; Quinidine Quaternary Ammonium Salt
EINECS	Contact for details

Quality Control

Our Quinidine Methiodide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of related substances and residual solvents, to ensure it meets high-purity standards suitable for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.