Description

Riboflavin, [3H(G)] CAS NO 42880-33-1 is a tritium-labeled derivative of riboflavin (Vitamin B2), a vital cofactor in numerous metabolic redox reactions. This radiolabeled compound is an indispensable tool for researchers requiring precise metabolic pathway tracing and bioavailability studies. It is primarily utilized by the pharmaceutical, nutritional science, and biochemical research sectors to investigate vitamin transport, enzyme kinetics, and drug-nutrient interactions.

Application

• Metabolic Pathway Tracing: Used as a radioactive tracer to study the absorption, distribution, metabolism, and excretion (ADME) of riboflavin in vivo and in vitro.
• Biochemical Research: Essential for investigating the mechanisms of flavoenzymes and flavocoenzymes (FMN, FAD) in redox reactions.
• Pharmaceutical Development: Employed in preclinical studies to assess the bioavailability and pharmacokinetics of new drug formulations containing or affecting Vitamin B2.
• Nutritional Science Studies: Facilitates research into riboflavin deficiency, fortification strategies, and nutrient uptake in various biological systems.
• Receptor Binding Assays: Serves as a ligand in studies targeting riboflavin transporters and binding proteins.

Basic Information

Product Name	Riboflavin, [3H(G)]
CAS No.	42880-33-1
Molecular Formula	C₁₇H₂₀N₄O₆ (³H labeled)
Molecular Weight	~378.4 g/mol (³H labeled)
Synonyms	Tritiated Riboflavin; Vitamin B2 (³H); 7,8-Dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]benzo[g]pteridine-2,4(3H,10H)-dione (³H); [³H]Riboflavin; Riboflavin-³H; Lactoflavin (³H); 6,7-Dimethyl-9-(D-1-ribityl)isoalloxazine (³H)
EINECS	Contact for details

Quality Control

Every batch of our radiolabeled compounds is produced and tested to meet the stringent requirements of research and development. Radiochemical purity and specific activity are critically assessed using validated methods such as HPLC with radiometric detection. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing the specific activity (Ci/mmol or GBq/mmol), radiochemical purity, chemical purity, and solvent specifications. Our quality system ensures traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C in the original solvent as specified on the label. For long-term storage, keep at -70°C to -80°C. The product is light-sensitive and should be handled under appropriate conditions to minimize decomposition. Always follow local regulations for the safe handling and disposal of radioactive materials.

Specification

Item	Specification
Appearance	Yellow to Orange Solution
Identification (HPLC)	Conforms to Reference Standard
Specific Activity	10-30 Ci/mmol (Contact for exact value)
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 98%
Solvent	Ethanol:Water (Specified on COA)
Concentration	1.0 mCi/mL (Contact for exact value)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.