Description

2-Iodo-5-Methylbenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an iodine substituent and a nitrile group on a methylbenzene ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and as a precursor to various functional groups.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the reactivity of the iodine atom.
• Ligand and Material Science Precursor: Serves as a starting material for the preparation of specialized ligands for catalysis and advanced organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new synthetic pathways in medicinal chemistry.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized dyes and functional colorants due to its aromatic core and modifiable functional groups.

Basic Information

Product Name	2-Iodo-5-Methylbenzonitrile
CAS No.	42872-86-6
Molecular Formula	C8H6IN
Molecular Weight	243.05 g/mol
Synonyms	5-Methyl-2-iodobenzonitrile; 2-Iodo-5-methylbenzenecarbonitrile; 2-Cyano-4-iodotoluene; Benzonitrile, 2-iodo-5-methyl-; 42872-86-6; 2-Iodo-5-methyl-benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Iodo-5-Methylbenzonitrile is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residue on Ignition	<0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.