Description

2-Bromo-5-Methylbenzonitrile is a versatile brominated aromatic nitrile compound that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and a nitrile group, makes it a valuable intermediate for constructing complex molecules with high precision. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzonitrile core.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and pesticides, where the bromine atom allows for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic and R&D Laboratories: Used in methodological research and for exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	2-Bromo-5-Methylbenzonitrile
CAS No.	42872-83-3
Molecular Formula	C8H6BrN
Molecular Weight	196.05 g/mol
Synonyms	5-Methyl-2-bromobenzonitrile; 2-Bromo-5-methylbenzenecarbonitrile; 2-Bromo-p-tolunitrile; Benzonitrile, 2-bromo-5-methyl-; 2-Bromo-5-tolyl cyanide; o-Bromo-p-tolunitrile; 2-Bromo-5-methyl-benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Methylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	65 - 70 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.