Description

3-Bromo-4-Methylbenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and nitrile functional groups, makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functional agrochemicals. We supply this high-purity intermediate with a focus on batch-to-batch consistency and reliable global logistics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its halogen and nitrile reactivity.
• Liquid Crystal Materials: Serves as a precursor for mesogenic compounds used in display technologies (LCDs).
• Organic Electronic Materials: Intermediate in the synthesis of electron-transport materials for OLEDs and other organic semiconductor applications.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Functional Dye and Pigment Synthesis: Used to introduce specific substituents into complex aromatic systems for colorant development.

Basic Information

Product Name	3-Bromo-4-Methylbenzonitrile
CAS No.	42872-74-2
Molecular Formula	C8H6BrN
Molecular Weight	196.05 g/mol
Synonyms	4-Methyl-3-bromobenzonitrile; 3-Bromo-p-tolunitrile; 3-Bromo-4-methylbenzenecarbonitrile; Benzonitrile, 3-bromo-4-methyl-; 3-Bromo-4-methyl-benzonitril; 3-Bromo-4-methylbenzonitrile (primary name)
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Methylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored in amber glass or opaque containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	65 - 68 °C
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.