Description

(S)-n-Carbobenzoxyl-N,n-Dimethyl-L-Prolinamide is a high-purity chiral proline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a protected, functionalized scaffold that enables the stereoselective construction of complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-quality, reliable intermediates for peptide mimetics, protease inhibitors, and other bioactive compound synthesis.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting proteases and requiring proline-based motifs.
• Peptidomimetic Research: Used in the design and development of peptide analogs and mimetics to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereocontrolled reactions to introduce defined stereochemistry.
• Agrochemical Synthesis: Intermediate in the production of certain chiral agrochemicals where specific stereochemistry impacts biological activity.
• Academic & R&D Laboratories: Serves as a reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals and catalysts.

Basic Information

Product Name	(S)-n-Carbobenzoxyl-N,n-Dimethyl-L-Prolinamide
CAS No.	42718-55-8
Molecular Formula	C16H22N2O3
Molecular Weight	290.36 g/mol
Synonyms	(S)-N-Carbobenzoxy-N,N-dimethyl-L-prolinamide; Cbz-N,N-Dimethyl-L-prolinamide; Z-N,N-Dimethyl-L-prolinamide; (S)-1-[(Benzyloxy)carbonyl]-N,N-dimethyl-L-prolineamide; (S)-N-Cbz-N,N-Dimethylprolinamide; L-Prolinamide, N-[(phenylmethoxy)carbonyl]-N,N-dimethyl-, (S)-; N-Carbobenzyloxy-N,N-dimethyl-L-prolinamide; Z-Dimethyl-L-prolinamide
EINECS	Contact for details

Quality Control

Our (S)-n-Carbobenzoxyl-N,n-Dimethyl-L-Prolinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and production applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.