Description

Methyl 2-Amino-2-(4-Fluorophenyl)Acetate Hydrochloride is a high-purity, pharmaceutically relevant intermediate, primarily valued for its role as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Its structural features make it a critical precursor for developing compounds with specific biological activity, particularly in central nervous system (CNS) and cardiovascular therapeutic areas. This compound is essential for R&D laboratories and production facilities in the pharmaceutical and fine chemical industries seeking reliable, high-quality synthetic intermediates.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex APIs, particularly those targeting neurological and cardiovascular disorders.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing novel molecules with fluorinated aromatic systems.
• Peptidomimetic Chemistry: Serves as a protected amino acid derivative for the preparation of peptide analogs and mimetics.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced agrochemicals and pesticides.
• Reference Standard: Suitable for use as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Methyl 2-Amino-2-(4-Fluorophenyl)Acetate Hydrochloride
CAS No.	42718-18-3
Molecular Formula	C9H11FNO2·HCl
Molecular Weight	219.65 g/mol (Free base: 183.19 g/mol)
Synonyms	Methyl (4-Fluorophenyl)glycinate Hydrochloride; 2-Amino-2-(4-fluorophenyl)acetic acid methyl ester hydrochloride; Methyl α-amino-4-fluorophenylacetate hydrochloride; 4-Fluoro-DL-phenylglycine methyl ester hydrochloride; (RS)-2-Amino-2-(4-fluorophenyl)acetic acid methyl ester hydrochloride; Methyl 2-amino-2-(p-fluorophenyl)acetate hydrochloride; DL-4-Fluorophenylglycine methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-2-(4-Fluorophenyl)Acetate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the stringent requirements of pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.