Description

Protein C is a critical vitamin K-dependent glycoprotein that functions as a key physiological anticoagulant, playing an essential role in regulating blood coagulation and maintaining vascular integrity. Its primary value lies in its ability to inactivate specific clotting factors, thereby preventing excessive and potentially dangerous thrombus formation. This product is vital for research and development in the life sciences, diagnostic manufacturing, and the production of therapeutic agents targeting coagulation disorders.

Application

• Biochemical Research & Development: Used as a standard or reagent in studies of the coagulation cascade, fibrinolysis, and vascular biology.
• In Vitro Diagnostic (IVD) Manufacturing: A key component in the production of calibrators, controls, and test kits for clinical assays measuring Protein C activity or antigen levels.
• Therapeutic Development: Serves as a starting material or reference standard in the development of plasma-derived or recombinant Protein C concentrates for treating congenital or acquired deficiencies.
• Quality Control in Plasma Fractionation: Employed as a reference material to monitor the purification and potency of plasma-derived products.
• Cell Culture & Biomedical Studies: Utilized in research exploring the role of the Protein C pathway in inflammation, apoptosis, and endothelial cell function.

Basic Information

Product Name	Protein C
CAS No.	42617-41-4
Molecular Formula	Contact for details
Molecular Weight	~62,000 Da (Glycosylated form)
Synonyms	Autoprothrombin IIA; Blood Coagulation Factor XIV; Coagulation Factor XIV; Anticoagulant Protein C; Activated Protein C (APC); PROC; Plasma Protein C; Vitamin K-Dependent Protein C
EINECS	Contact for details

Quality Control

Our Protein C is manufactured and tested under stringent quality management systems. Each lot is characterized for identity, purity, and biological activity using advanced analytical techniques. Certificates of Analysis (COA) detailing specific results for purity (by SDS-PAGE and HPLC), activity (chromogenic or clotting assay), and other critical parameters are provided to ensure it meets the rigorous standards required for research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive) and should be handled under controlled, dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (SDS-PAGE / Immunoassay)	Conforms
Purity (SDS-PAGE, reduced)	≥ 90%
Assay (Functional Activity)	≥ 80% of stated value
Endotoxin	< 1.0 EU/μg
Moisture (for lyophilized form)	< 3.0%
Solubility	Clear, colorless solution at specified concentration

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.