Description

L-Methionine γ-Lyase is a highly specific pyridoxal 5'-phosphate (PLP)-dependent enzyme that catalyzes the α,γ-elimination of L-methionine and related sulfur-containing amino acids. This unique catalytic activity makes it an indispensable tool for biochemical research, enzymatic analysis, and the development of diagnostic assays. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and biotechnology sectors.

Application

• Biochemical Research: A critical reagent for studying sulfur amino acid metabolism, enzyme kinetics, and reaction mechanisms.
• Diagnostic Kit Development: Used as a key component in enzymatic assays for the specific detection and quantification of L-methionine in biological samples.
• Pharmaceutical R&D: Employed in drug discovery programs targeting metabolic pathways involving methionine, such as in cancer research.
• Enzyme Engineering: Serves as a model enzyme for protein engineering studies aimed at altering substrate specificity or improving catalytic efficiency.
• Food & Nutrition Analysis: Applied in methods to determine methionine content in foodstuffs, supplements, and animal feed.
• Academic Teaching: Used in advanced biochemistry laboratories to demonstrate principles of enzyme catalysis and inhibition.

Basic Information

Product Name	L-Methionine γ-Lyase
CAS No.	42616-25-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Methioninase; L-Methionine γ-lyase; Methionine γ-lyase; MGL; EC 4.4.1.11; L-Methionine methanethiol-lyase (deaminating); L-Methionine γ-lyase (deaminating)
EINECS	Contact for details

Quality Control

Our L-Methionine γ-Lyase is produced and tested under stringent quality management systems. Each lot undergoes comprehensive analysis to ensure high specific activity, purity, and stability. A detailed Certificate of Analysis (COA) is provided, reporting key parameters such as activity, protein content, and purity. We support research and industrial applications requiring consistent, reliable enzymatic performance.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (IR)	Complies
Specific Activity	≥ [Value] U/mg protein
Protein Content (Biuret)	≥ [Value] %
Purity (SDS-PAGE)	≥ [Value] %
pH (in solution)	6.0 - 8.0
Endotoxin (LAL)	< 1.0 EU/μg protein (if required)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.