Description

3-Hydroxyoctadecanoyl-Coenzyme A is a key biochemical intermediate in fatty acid metabolism, specifically in the β-oxidation pathway. This high-purity compound is essential for research and development in metabolic studies and enzyme function analysis. It is primarily utilized by biochemists, pharmaceutical researchers, and diagnostic manufacturers working on lipid metabolism disorders, enzyme kinetics, and metabolic pathway engineering.

Application

• Biochemical Research: Used as a critical substrate for studying the enzymatic activity of hydroxyacyl-CoA dehydrogenases and other enzymes involved in fatty acid β-oxidation.
• Pharmaceutical Development: Serves as a reference standard and intermediate in the research of metabolic diseases, such as disorders of mitochondrial fatty acid oxidation.
• Diagnostic Reagent Manufacturing: Employed in the formulation of in-vitro diagnostic (IVD) kits and assays designed to measure specific enzyme deficiencies or metabolic biomarkers.
• Enzyme Kinetics & Inhibition Studies: Acts as a precise tool for determining kinetic parameters (Km, Vmax) and for screening potential inhibitors of metabolic enzymes.
• Metabolomics & Pathway Analysis: Used in targeted metabolomics to map and quantify flux through specific lipid metabolic pathways in cell cultures or tissue samples.
• Academic & Institutional Research: Provides a well-defined biochemical tool for universities and research institutes focusing on lipid biochemistry and cellular energy metabolism.

Basic Information

Product Name	3-Hydroxyoctadecanoyl-Coenzyme A
CAS No.	42578-91-6
Molecular Formula	C39H68N7O19P3S
Molecular Weight	1063.96 g/mol
Synonyms	3-Hydroxystearoyl-Coenzyme A; 3-Hydroxyoctadecanoyl-CoA; 3-Hydroxy-C18:0-CoA; 3-Hydroxystearoyl-CoA; (3R)-3-Hydroxyoctadecanoyl-CoA; 3-Hydroxyacyl-Coenzyme A (C18); β-Hydroxyoctadecanoyl-Coenzyme A; 3-Hydroxy fatty acyl-CoA (C18)
EINECS	Contact for details

Quality Control

Our 3-Hydroxyoctadecanoyl-Coenzyme A is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via mass spectrometry (MS) and NMR. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reliable and reproducible results for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated at -70°C. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity	Tested as suitable substrate for target enzyme

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.