Description

12-Chloro-5-Dodecyne is a versatile alkyne-containing organic intermediate characterized by its terminal chloro and internal alkyne functional groups. This unique bifunctional structure makes it a valuable building block for synthesizing complex molecules in advanced research and industrial applications. It is particularly essential for chemists and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require precise molecular scaffolds for drug discovery, ligand synthesis, and polymer modification.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those requiring alkyne moieties for click chemistry or as structural components.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators where the chloro and alkyne groups enable specific bioactivity.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers, dendrimers, and functionalized surfaces with tailored properties.
• Ligand and Catalyst Preparation: Employed in organometallic chemistry for the preparation of specialized ligands and catalysts used in asymmetric synthesis and coupling reactions.
• Chemical Biology Probes: Utilized to create molecular probes and tags for bio-conjugation and labeling studies due to its reactive functional handles.
• Organic Synthesis Building Block: A fundamental starting material for constructing more complex organic molecules through Sonogashira, substitution, and cyclization reactions.

Basic Information

Product Name	12-Chloro-5-Dodecyne
CAS No.	42513-36-0
Molecular Formula	C₁₂H₂₁Cl
Molecular Weight	200.75 g/mol
Synonyms	5-Dodecyn-12-ol, 12-chloro-; 12-Chloro-5-dodecyne; 12-Chloro-5-dodecyn-1-ol; 1-Chloro-10-undecyne; 12-Chloro-1-dodecyne-5-yne; 12-Chlorododec-5-yne; 5-Dodecyn-1-ol, 12-chloro-
EINECS	Contact for details

Quality Control

Our 12-Chloro-5-Dodecyne is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.