Description

3-Bromo-n-(tert-Butyl)Benzamide 97% is a high-purity organic building block featuring a brominated aromatic ring and a sterically hindered tert-butyl amide group. This compound matters as a versatile intermediate for advanced synthesis, enabling the introduction of both halogen and amide functionalities in a single step. It is needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in medicinal chemistry for lead optimization and library synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, especially in kinase inhibitor and protease inhibitor research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the bromine atom for further functionalization.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and liquid crystals, where the bulky tert-butyl group can influence material properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a precursor for generating other functionalized benzamides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein-ligand interactions.

Basic Information

Product Name	3-Bromo-n-(tert-Butyl)Benzamide 97%
CAS No.	42498-39-5
Molecular Formula	C11H14BrNO
Molecular Weight	256.14 g/mol
Synonyms	3-Bromo-N-(tert-butyl)benzamide; N-tert-Butyl-3-bromobenzamide; 3-Bromo-N-(1,1-dimethylethyl)benzamide; Benzamide, 3-bromo-N-(1,1-dimethylethyl)-; 3-Bromobenzamide, N-tert-butyl-; 42498-39-5; tert-Butyl 3-bromobenzamide; 3-Bromo-N-tert-butylbenzamide
EINECS	Contact for details

Quality Control

Our 3-Bromo-n-(tert-Butyl)Benzamide 97% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the specified 97% minimum purity. Certificates of Analysis (COA) with full batch traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and stored under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.