Description

n-(1,1-Dimethylethyl)-4-Iodobenzamide is a high-purity, specialized organic intermediate featuring a tert-butyl amide group and an iodine substituent on the aromatic ring. This compound is valued for its role as a versatile building block in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is primarily sought by research institutions and industrial manufacturers engaged in the synthesis of complex molecules, where its unique structure facilitates coupling reactions and serves as a key precursor.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting neurological disorders or acting as enzyme inhibitors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging the iodine atom for further functionalization.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: The aryl iodide moiety makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings to form complex biaryl systems.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Acts as a probe or labeling agent in biochemical research due to its potential for radiolabeling or further bioconjugation.

Basic Information

Product Name	n-(1,1-Dimethylethyl)-4-Iodobenzamide
CAS No.	42498-36-2
Molecular Formula	C11H14INO
Molecular Weight	303.14 g/mol
Synonyms	4-Iodo-N-tert-butylbenzamide; N-tert-Butyl-4-iodobenzamide; p-Iodo-N-tert-butylbenzamide; 4-Iodobenzoic acid tert-butylamide; tert-Butyl 4-iodobenzamide; N-(tert-Butyl)-4-iodobenzamide; Benzamide, N-(1,1-dimethylethyl)-4-iodo-
EINECS	Contact for details

Quality Control

Our n-(1,1-Dimethylethyl)-4-Iodobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee consistent quality and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.