Description

n-(tert-Butyl)-4-Methylbenzamide is a specialized organic compound belonging to the class of substituted benzamides. This chemical serves as a valuable intermediate and building block in advanced organic synthesis, offering a unique sterically hindered tert-butyl amide group. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, agrochemicals, and functional materials. Its specific structure makes it a key precursor for creating molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or as a component of peptidomimetics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators, where the tert-butyl group can influence bioavailability and metabolic stability.
• Material Science: Acts as a monomer or modifier in the production of specialty polymers, resins, and liquid crystals to impart specific thermal or mechanical properties.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories as a versatile intermediate for constructing complex molecular architectures, including natural product analogs.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions due to its amide linkage and aromatic ring.

Basic Information

Product Name	n-(tert-Butyl)-4-Methylbenzamide
CAS No.	42498-32-8
Molecular Formula	C12H17NO
Molecular Weight	191.27 g/mol
Synonyms	4-Methyl-N-(tert-butyl)benzamide; N-tert-Butyl-4-methylbenzamide; p-Toluic acid tert-butylamide; N-(1,1-Dimethylethyl)-4-methylbenzamide; 4-Methylbenzoic acid tert-butylamide; tert-Butyl 4-methylbenzamide; N-(tert-Butyl)-p-toluamide
EINECS	Contact for details

Quality Control

Our n-(tert-Butyl)-4-Methylbenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.