Description

Fluoro-Methanesulfonyl Chloride is a highly reactive fluorinated sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to introduce the versatile fluoro-methanesulfonyl (FMS) group, enabling the creation of novel compounds with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key reagent for synthesizing sulfonamide-based drugs, enzyme inhibitors, and novel bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides with enhanced efficacy.
• Polymer & Material Science: Serves as a monomer or modifier for creating specialty polymers, coatings, and fluorinated materials with unique surface properties.
• Ligand & Catalyst Development: Employed in the design of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A versatile electrophile for introducing the FMS group in medicinal chemistry and process development.
• Dye & Pigment Manufacturing: Intermediate for producing specialized colorants and photographic chemicals.

Basic Information

Product Name	Fluoro-Methanesulfonyl Chloride
CAS No.	42497-69-8
Molecular Formula	CH2ClFO2S
Molecular Weight	132.54 g/mol
Synonyms	Fluoromethanesulfonyl chloride; Fluoromethylsulfonyl chloride; FMS-Cl; Monofluoromethanesulfonyl chloride; Fluoromethanesulphonyl chloride; Fluoromethylsulphonyl chloride; (Fluoromethyl)sulfonyl chloride; 1-Fluoro-1-methanesulfonyl chloride
EINECS	Contact for details

Quality Control

Our Fluoro-Methanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay (GC/HPLC), identity confirmation (IR, NMR), and impurity profiling, to ensure it meets the high-purity standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C (refrigerated) or as specified on the label. Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.