Description

4-Acetylphenylacetylene is a versatile aromatic acetylene derivative featuring both an acetyl and an alkyne functional group on a benzene ring. This unique bifunctional structure makes it a valuable high-purity building block for advanced organic synthesis and materials science research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring acetylene-linked aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate acetylene motifs.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers, conductive materials, and metal-organic frameworks (MOFs).
• Click Chemistry: An ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, enabling efficient bioconjugation and polymer functionalization.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and coordination chemistry.
• Organic Electronic Materials: Investigated as a building block for organic semiconductors and light-emitting materials due to its conjugated system.

Basic Information

Product Name	4-Acetylphenylacetylene
CAS No.	42472-69-5
Molecular Formula	C10H8O
Molecular Weight	144.17 g/mol
Synonyms	1-(4-Ethynylphenyl)ethanone; 4-Ethynylacetophenone; p-Acetylphenylacetylene; 4-Acetylethynylbenzene; 4-Ethynyl Acetophenone; 1-(4-Ethynylphenyl)ethan-1-one; 4-Acetylphenylethyne
EINECS	Contact for details

Quality Control

Our 4-Acetylphenylacetylene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is light-sensitive and should be stored away from direct light exposure. Keep container tightly sealed when not in use to minimize moisture uptake and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	65 - 70 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.