Description

Carbamic Acid, (Phenylmethyl)-, 1,1-Dimethylethyl Ester (9Ci) is a protected amine derivative, specifically a tert-butyl carbamate (Boc) protecting group reagent. This compound is a critical building block in organic synthesis, valued for its role in safeguarding amine functionalities during complex multi-step reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for peptide synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key reagent for the introduction of the Boc protecting group in the synthesis of peptides and complex drug molecules.
• Organic Synthesis Building Block: Used in multi-step synthetic routes to protect primary amines, enabling selective reactions at other functional sites.
• Agrochemical Research: Serves as a precursor or intermediate in the development of novel herbicides, fungicides, and insecticides.
• Peptide Chemistry: Fundamental for solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and advanced materials.
• Academic & R&D Laboratories: Used in research for method development and the exploration of new synthetic pathways.

Basic Information

Product Name	Carbamic Acid, (Phenylmethyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	42116-44-9
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	N-(tert-Butoxycarbonyl)benzylamine; Benzyl tert-butylcarbamate; N-Boc-benzylamine; N-Benzyl-N-(tert-butoxycarbonyl)amine; tert-Butyl benzylcarbamate; Boc-Bn-NH2; (Phenylmethyl)carbamic acid 1,1-dimethylethyl ester; N-Cbz protected tert-butylamine (common misnomer)
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (Phenylmethyl)-, 1,1-Dimethylethyl Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	86 - 90 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.