Description

5-α-Androstan-17-β-Ol-3-One Glucosiduronate is a high-purity conjugated metabolite of dihydrotestosterone (DHT). This compound is of significant value as a critical reference standard and analytical reagent in biochemical research and pharmaceutical development. It is primarily required by research institutions, diagnostic laboratories, and pharmaceutical companies engaged in endocrinology studies, steroid metabolism profiling, and the development of assays for androgen-related biomarkers.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification of DHT metabolites in biological samples via LC-MS/MS or GC-MS.
• Clinical Diagnostics: Serves as a calibrator in the development and validation of diagnostic tests for hormonal disorders, such as 5-α-reductase deficiency.
• Biochemical Research: Essential for studying androgen metabolism pathways, enzyme kinetics, and the glucuronidation process of steroid hormones.
• Doping Control: Employed as a reference compound in anti-doping laboratories for the precise detection of prohibited anabolic steroid metabolites in athletes.
• Metabolite Identification: Aids in the structural confirmation and identification of steroid glucuronides in drug metabolism and pharmacokinetics (DMPK) studies.

Basic Information

Product Name	5-α-Androstan-17-β-Ol-3-One Glucosiduronate
CAS No.	42037-24-1
Molecular Formula	C25H38O8
Molecular Weight	466.57 g/mol
Synonyms	5α-Androstan-17β-ol-3-one glucuronide; Dihydrotestosterone glucuronide; DHT glucuronide; 5α-Dihydrotestosterone 17β-D-glucuronide; Androstanolone glucuronide; 17β-Hydroxy-5α-androstan-3-one 17β-D-glucuronide; 5α-Androstane-3-one-17β-yl β-D-Glucopyranosiduronic Acid
EINECS	Contact for details

Quality Control

Our 5-α-Androstan-17-β-Ol-3-One Glucosiduronate is manufactured under strict quality control protocols suitable for research and analytical applications. Each batch is characterized using advanced spectroscopic and chromatographic techniques to ensure identity, purity, and stability. A comprehensive Certificate of Analysis (COA) is provided, detailing results for assay, related substances, and residual solvents, ensuring full traceability and compliance with our internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.