Description

2-Bromobutanenitrile is a versatile brominated nitrile compound that serves as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, where the bromine atom and the nitrile group act as handles for constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, enabling the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing heterocyclic structures or chiral centers.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its structure can be incorporated into novel bioactive molecules.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research and development of advanced polymers and liquid crystals, where the nitrile group can impart specific polarity and stability.
• Chemical Research: A valuable reagent for academic and industrial R&D in organic chemistry, facilitating carbon-carbon bond formation and functional group transformations.

Basic Information

Product Name	2-Bromobutanenitrile
CAS No.	41929-78-6
Molecular Formula	C4H6BrN
Molecular Weight	148.00 g/mol
Synonyms	2-Bromobutyronitrile; Butanenitrile, 2-bromo-; α-Bromobutyronitrile; 2-Bromo-n-butyronitrile; NSC 404058; 2-Bromobutane nitrile; (RS)-2-Bromobutanenitrile; (±)-2-Bromobutanenitrile
EINECS	Contact for details

Quality Control

Our 2-Bromobutanenitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including Certificates of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, strong oxidizing agents, and reducing agents. Recommended storage temperature is 2-8°C for long-term stability. The product is moisture-sensitive; keep container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%
Specific Gravity (20°C)	1.45 - 1.55
Refractive Index (n20D)	1.470 - 1.480

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.