Description

4'-n-Piperidinophenyl Acetylene is a specialized organic building block featuring a terminal alkyne group linked to a piperidine-substituted phenyl ring. This unique molecular architecture makes it a valuable intermediate for constructing complex molecules in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for applications such as medicinal chemistry, drug discovery, and material science.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional materials.
• Chemical Biology: Employed in bioconjugation and probe development via click chemistry (e.g., CuAAC) due to its terminal alkyne functionality.
• Academic & Industrial R&D: A versatile building block for exploring new chemical spaces and synthesizing complex heterocyclic compounds.

Basic Information

Product Name	4'-n-Piperidinophenyl Acetylene
CAS No.	41876-66-8
Molecular Formula	C₁₃H₁₅N
Molecular Weight	185.27 g/mol
Synonyms	1-(4-Ethynylphenyl)piperidine; 4-(Piperidin-1-yl)phenylacetylene; 4-Ethynyl-1-(1-piperidinyl)benzene; 4-(1-Piperidinyl)phenylacetylene; 1-(4-Ethynyl-phenyl)-piperidine; 4-Piperidin-1-yl-phenylacetylene; 4-Ethynyl-N-piperidinobenzene
EINECS	Contact for details

Quality Control

Our 4'-n-Piperidinophenyl Acetylene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.