Description

Tocainide CAS NO 41708-72-9 is a class IB antiarrhythmic agent and a primary amine analogue of lidocaine. It is valued for its oral bioavailability and its role as a sodium channel blocker, which stabilizes cardiac membranes and reduces abnormal electrical activity. This pharmaceutical intermediate is essential for researchers and manufacturers in the pharmaceutical and life sciences sectors developing treatments for ventricular arrhythmias.

Application

• Pharmaceutical Active Ingredient: Primary use as an oral antiarrhythmic drug for the management of ventricular arrhythmias.
• Chemical Synthesis Intermediate: Serves as a key building block in the research and development of novel sodium channel blockers and related therapeutic compounds.
• Pharmacological Research: Used in preclinical and clinical studies to investigate cardiac electrophysiology and mechanisms of arrhythmia suppression.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Academic Research: Utilized in university and institutional labs for biochemical and pharmacological studies related to ion channel function.

Basic Information

Product Name	Tocainide
CAS No.	41708-72-9
Molecular Formula	C11H16N2O
Molecular Weight	192.26 g/mol
Synonyms	2-Amino-2',6'-propionoxylidide; W-36095; Tonocard; Xylamide; 2-(2,6-Dimethylphenyl)amino-propionamide; 2',6'-Pipecoloxylidide; 1-Methyl-2-(2,6-xylylcarbamoyl)ethylamine
EINECS	255-500-2

Quality Control

Our Tocainide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets high-grade standards suitable for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.