Description

2-Bromo-2-Methylpropanenitrile is a versatile and highly reactive organic nitrile compound, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the tert-butyl nitrile moiety, a key functional group for constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, enabling the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a sterically hindered nitrile group.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where its structure contributes to biological activity.
• Polymer Chemistry: Acts as a functional monomer or initiator in the production of specialty polymers and resins with tailored properties.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and cyanoalkylation reactions to construct complex organic molecules in R&D laboratories.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Utilized in the development of advanced organic electronic materials and liquid crystals.

Basic Information

Product Name	2-Bromo-2-Methylpropanenitrile
CAS No.	41658-69-9
Molecular Formula	C5H8BrN
Molecular Weight	162.03 g/mol
Synonyms	2-Bromo-2-methylpropionitrile; (2-Bromo-2-methylpropyl) cyanide; α-Bromoisobutyronitrile; Bromoisobutyronitrile; 2-Bromo-2-methylpropanenitrile; 2-Methyl-2-bromopropionitrile; tert-Butyl bromocyanide; AIBN analog (bromo)
EINECS	Contact for details

Quality Control

Our 2-Bromo-2-Methylpropanenitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for critical industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents. Due to its reactivity, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.40 g/cm³
Refractive Index	~1.46

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.