Description

4-Bromo-2-Fluorobiphenyl is a high-purity halogenated biphenyl derivative, a key building block in advanced organic synthesis. Its precise molecular architecture makes it an indispensable intermediate for the development of complex, high-value chemical products. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the biphenyl core provides structural stability and bioactivity.
• Liquid Crystal & OLED Materials: Acts as a foundational unit for creating advanced organic electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Ligand & Catalyst Development: Employed in organometallic chemistry for the preparation of specialized ligands used in cross-coupling reactions like Suzuki-Miyaura couplings.
• Polymer & Resin Modifier: Incorporated into polymer chains to impart specific properties such as flame retardancy, thermal stability, or altered refractive index.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science research, enabling the exploration of new chemical entities.

Basic Information

Product Name	4-Bromo-2-Fluorobiphenyl
CAS No.	41604-19-7
Molecular Formula	C12H8BrF
Molecular Weight	251.10 g/mol
Synonyms	2-Fluoro-4-bromobiphenyl; 1-Bromo-4-(2-fluorophenyl)benzene; 4-Bromo-2-fluorodiphenyl; Biphenyl, 4-bromo-2-fluoro-; [1,1'-Biphenyl]-4-bromo-2-fluoro-; 2-Fluorophenyl-4-bromobenzene; 4-Bromo-2'-fluorobiphenyl
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorobiphenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure a purity typically exceeding 98.0% and compliance with stringent internal specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.