Description

Cefsulodin Sodium is a semi-synthetic, β-lactamase-resistant cephalosporin antibiotic. This compound is valued for its specific and potent activity against Pseudomonas aeruginosa, making it a critical tool in microbiological research and quality control. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic manufacturers, and academic institutions for susceptibility testing, antimicrobial assay development, and as a reference standard. Cefsulodin Sodium CAS NO 41444-66-0 is essential for ensuring the accuracy and reliability of microbiological methods.

Application

• Microbiological Reference Standard: Used as a certified reference material (CRM) for calibrating equipment and validating analytical methods in pharmaceutical quality control labs.
• Antimicrobial Susceptibility Testing (AST): A key component in culture media and discs for determining the sensitivity of Pseudomonas aeruginosa and other Gram-negative bacteria.
• Research & Development: Employed in biochemical and pharmacological studies to investigate bacterial resistance mechanisms and the efficacy of β-lactam antibiotics.
• Diagnostic Manufacturing: Incorporated into selective agar plates and diagnostic kits for the identification and isolation of specific bacterial pathogens.
• Pharmaceutical Intermediates: Serves as a starting material or intermediate in the synthesis of more complex antibiotic formulations for clinical use.

Basic Information

Product Name	Cefsulodin Sodium
CAS No.	41444-66-0
Molecular Formula	C22H19N4O8S2•Na
Molecular Weight	554.53 g/mol
Synonyms	Cefsulodin; Cefsulodine Sodium; Sodium Cefsulodin; SCE-129; CGP-7174/E; (6R,7R)-7-[(R)-2-(4-Carbamoylpyridin-1-ium-1-yl)acetamido]-8-oxo-3-[(pyridin-1-ium-4-ylsulfanyl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Antibiotic SCE-129; Cefsulodin Sodium Salt
EINECS	Contact for details

Quality Control

Our Cefsulodin Sodium is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent limits for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with pharmaceutical research and reference standard requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
pH (1% Solution)	4.5 - 6.5
Specific Optical Rotation	+15° to +25° (c=1 in H2O)
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.