Description

5-(4-Fluorophenyl)-1,3,4-Oxadiazole-2(3H)-Thione is a high-value heterocyclic building block featuring a fluorinated aromatic ring and a reactive oxadiazole-thione core. This compound is essential for advanced research and development in medicinal chemistry, serving as a versatile precursor for synthesizing novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas targeting enzymes and receptors where the fluorophenyl and oxadiazole motifs are beneficial.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a building block for creating specialized polymers, ligands for catalysis, or organic electronic materials.
• Biochemical Probe Development: Utilized in designing molecular probes and inhibitors for studying biological pathways and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects.

Basic Information

Product Name	5-(4-Fluorophenyl)-1,3,4-Oxadiazole-2(3H)-Thione
CAS No.	41421-13-0
Molecular Formula	C8H5FN2OS
Molecular Weight	196.20 g/mol
Synonyms	5-(4-Fluorophenyl)-1,3,4-oxadiazole-2-thiol; 2-Mercapto-5-(4-fluorophenyl)-1,3,4-oxadiazole; 5-(p-Fluorophenyl)-1,3,4-oxadiazole-2(3H)-thione; 4-Fluorophenyl-1,3,4-oxadiazole-2-thione; 41421-13-0; 5-(4-Fluorophenyl)-2-mercapto-1,3,4-oxadiazole; 2-Thioxo-5-(4-fluorophenyl)-2,3-dihydro-1,3,4-oxadiazole
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenyl)-1,3,4-Oxadiazole-2(3H)-Thione is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.