Description

Pancuronium Bromide Related Compound B is a high-purity chemical reference standard, identified by CAS NO 41261-71-6. This compound is critically important for ensuring the quality, safety, and efficacy of pharmaceutical products, particularly neuromuscular blocking agents. It is primarily required by analytical laboratories and pharmaceutical manufacturers for use in research, method development, and rigorous quality control testing.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of impurities in Pancuronium Bromide active pharmaceutical ingredient (API) and finished drug products.
• Analytical Method Development & Validation: Essential for developing and validating sensitive HPLC, UPLC, or LC-MS methods to monitor related substances.
• Quality Control & Assurance (QC/QA): A critical tool for in-process testing and release testing of batches to ensure compliance with pharmacopeial monographs (e.g., USP, EP, BP).
• Stability Studies: Employed to track the formation of degradation products under various stress conditions, supporting shelf-life determination.
• Regulatory Submissions: Provides necessary impurity characterization data for drug master files (DMFs), investigational new drug (IND) applications, and new drug applications (NDA).
• Academic & Contract Research: Supports pharmacological and toxicological research studies in academic institutions and CROs (Contract Research Organizations).

Basic Information

Item	Details
Product Name	Pancuronium Bromide Related Compound B
CAS No.	41261-71-6
Molecular Formula	C23H38BrNO4
Molecular Weight	472.46 g/mol
Synonyms	3α,17β-Diacetoxy-2β,16β-dipiperidino-5α-androstane Bromide; 2β,16β-Dipiperidino-5α-androstane-3α,17β-diol Diacetate Bromide; Pancuronium Bromide Impurity B; Pancuronium Related Compound B; 5α-Androstane-3α,17β-diol, 2,16-bis(1-piperidinyl)-, diacetate, bromide (1:1); Pancuronium Bromide EP Impurity B
EINECS	Contact for details

Quality Control

Every batch of Pancuronium Bromide Related Compound B is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to support its use as a reference standard, including chromatographic purity, structural confirmation, and quantitative assay. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting compliance with in-house specifications aligned with pharmacopeial expectations. Our quality commitment ensures traceability, reliability, and consistency for your critical analytical workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent absorption of water vapor.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.