Description

3,3-Difluoropentanedioic Acid is a high-purity fluorinated dicarboxylic acid building block of significant interest in advanced organic synthesis. This compound matters for its unique structural motif, which introduces both fluorine atoms and a reactive diacid functionality into target molecules, enabling the fine-tuning of physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), where fluorine substitution can enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging fluorine's ability to improve lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel fluorinated ligands and metal-organic frameworks (MOFs) with tailored catalytic properties.
• Polymer Modification: Incorporated as a monomer or cross-linking agent to produce specialty fluorinated polymers with enhanced chemical resistance, thermal stability, or surface properties.
• Material Science Research: Employed in the development of advanced materials, such as liquid crystals, electrolytes for batteries, and organic semiconductors.
• Peptide Mimetics: Useful in medicinal chemistry for creating fluorinated peptide analogs that are more resistant to enzymatic degradation.

Basic Information

Product Name	3,3-Difluoropentanedioic Acid
CAS No.	41131-19-5
Molecular Formula	C5H6F2O4
Molecular Weight	168.10 g/mol
Synonyms	3,3-Difluoroglutaric Acid; Difluoroglutaric Acid; Pentanedioic acid, 3,3-difluoro-; 3,3-Difluoropentanedioic acid; Glutaric acid, 3,3-difluoro-; 41131-19-5; 3,3-Difluoropentanedioicacid
EINECS	Contact for details

Quality Control

Our 3,3-Difluoropentanedioic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency, suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.