Description

Z-Gly-Gly-Nhnh-Boc is a protected peptide derivative and a key building block in solid-phase peptide synthesis (SPPS). This compound is specifically designed for the controlled elongation of peptide chains, offering a reactive hydrazide group protected by a Boc (tert-butoxycarbonyl) moiety. It is an essential intermediate for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the sequential assembly of custom peptides.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs) for peptide drugs.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Proteomics Research: Employed in the synthesis of peptide standards, probes, and enzyme substrates.
• Combinatorial Chemistry: A valuable reagent for generating diverse peptide libraries for drug discovery screening.
• Material Science: Potential use in creating peptide-functionalized polymers and biomaterials.

Basic Information

Product Name	Z-Gly-Gly-Nhnh-Boc
CAS No.	40847-16-3
Molecular Formula	C₁₇H₂₄N₄O₆
Molecular Weight	380.40 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]glycylglycine 2-[(1,1-Dimethylethoxy)carbonyl]hydrazide; Z-Gly-Gly-NHNH-Boc; Z-Gly-Gly-NHNH-t-Boc; Boc-Hydrazide of Z-Gly-Gly; Nα-Carbobenzoxy-glycyl-glycyl-N'-tert-butoxycarbonyl hydrazide; Glycine, N-[(phenylmethoxy)carbonyl]glycyl-, 2-[(1,1-dimethylethoxy)carbonyl]hydrazide; CBZ-Gly-Gly-NHNH-Boc
EINECS	Contact for details

Quality Control

Our Z-Gly-Gly-Nhnh-Boc is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.