Description

Z-D-Tyrosinol, 97 CAS NO 40829-66-1 is a high-purity, non-natural amino acid derivative featuring a D-configuration at the tyrosine α-carbon and a reduced carboxyl group to an alcohol. This specific chiral building block is critical for the synthesis of complex peptides and peptidomimetics with enhanced metabolic stability. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced drug discovery, particularly for developing enzyme inhibitors, receptor ligands, and novel therapeutic peptides.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based therapeutics and enzyme inhibitors.
• Peptidomimetic Synthesis: Used to construct peptide analogs where the D-configuration and alcohol functionality provide resistance to proteolytic degradation.
• Bioconjugation & Probe Development: Serves as a building block for creating labeled peptides or affinity probes for biochemical and diagnostic research.
• Academic & Industrial R&D: Essential for medicinal chemistry programs focusing on structure-activity relationship (SAR) studies of tyrosine-containing peptides.
• Catalyst & Ligand Preparation: Can be incorporated into the structure of chiral catalysts or ligands for asymmetric synthesis.

Basic Information

Product Name	Z-D-Tyrosinol, 97 CAS NO 40829-66-1
CAS No.	40829-66-1
Molecular Formula	C17H19NO5
Molecular Weight	317.34 g/mol
Synonyms	N-Carbobenzoxy-D-tyrosinol; Z-D-Tyr-ol; D-Tyrosinol, N-benzyloxycarbonyl-; (R)-2-(((Benzyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)propan-1-ol; N-Cbz-D-tyrosinol; Benzyl (R)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-ylcarbamate; CBZ-D-Tyrosinol; Z-D-Tyrosinol
EINECS	Contact for details

Quality Control

Our Z-D-Tyrosinol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and chiral analysis to confirm enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure it meets the stringent requirements of research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.