Description

Benzonitrile, 4-(Chloroacetyl)- (9Ci) is a versatile aromatic nitrile derivative that serves as a critical bifunctional building block in advanced organic synthesis. Its molecular structure, featuring both a reactive chloroacetyl group and a cyano group, makes it an essential intermediate for constructing complex heterocycles and pharmaceutical scaffolds. This high-purity compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where its aromatic core provides structural stability and bioactivity.
• Heterocyclic Chemistry: Serves as a fundamental building block for constructing pyridine, quinoline, and other nitrogen-containing heterocycles important in material science and medicinal chemistry.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and asymmetric synthesis.
• Polymer Modification: Acts as a functional monomer or cross-linking agent in the production of high-performance polymers and resins with specific thermal or chemical resistance properties.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	Benzonitrile, 4-(Chloroacetyl)- (9Ci)
CAS No.	40805-50-3
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	4-(Chloroacetyl)benzonitrile; 4-Chloroacetylbenzonitrile; 4-Cyanophenacyl Chloride; p-Chloroacetylbenzonitrile; 2-Chloro-1-(4-cyanophenyl)ethanone; 4-Cyanophenacyl chloride; 1-(4-Cyanophenyl)-2-chloroethanone; NSC 403697
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-(Chloroacetyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.