Description

5-Hexyn-2-One, 3-Hydroxy- (9Ci) is a specialized alkyne-containing ketone derivative that serves as a versatile chiral building block in advanced organic synthesis. Its unique structure, featuring both a hydroxyl group and a terminal alkyne, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring specific stereochemistry.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials.
• Click Chemistry: The terminal alkyne group enables its use in Huisgen 1,3-dipolar cycloaddition reactions for bioconjugation and polymer functionalization.
• Asymmetric Synthesis: Employed as a building block in catalytic asymmetric reactions to introduce chiral centers.
• Fine Chemical Production: Used in the multi-step synthesis of complex fragrance and flavor compounds.

Basic Information

Product Name	5-Hexyn-2-One, 3-Hydroxy- (9Ci)
CAS No.	40797-89-5
Molecular Formula	C6H8O2
Molecular Weight	112.13 g/mol
Synonyms	3-Hydroxy-5-hexyn-2-one; 5-Hexyn-2-one, 3-hydroxy-; 3-Hydroxyhex-5-yn-2-one; 1-Hexyn-4-one, 5-hydroxy-; 5-Hydroxy-1-hexyn-4-one
EINECS	Contact for details

Quality Control

Our 5-Hexyn-2-One, 3-Hydroxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.