Description

Benzeneacetonitrile, α-Amino-4-Bromo-, Hydrochloride (1:1) is a high-purity, halogenated amino nitrile hydrochloride salt, a key building block in advanced organic synthesis. This compound is valued for its dual functional groups, which enable its use in constructing complex molecular architectures, particularly in pharmaceutical research and development. It serves as a critical intermediate for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce bromine and amino functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A versatile building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of novel therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its bromine substituent for structural diversity.
• Peptide Mimetics & Conjugate Chemistry: The amino and nitrile groups facilitate its incorporation into peptide analogs and bioconjugates for drug discovery.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized monomers and polymers for advanced materials.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological mechanisms and pathways.

Basic Information

Product Name	Benzeneacetonitrile, α-Amino-4-Bromo-, Hydrochloride (1:1)
CAS No.	40658-53-5
Molecular Formula	C8H8BrN2•HCl
Molecular Weight	249.53 g/mol
Synonyms	4-Bromo-α-aminobenzeneacetonitrile hydrochloride; (4-Bromophenyl)glycinonitrile hydrochloride; 2-Amino-2-(4-bromophenyl)acetonitrile hydrochloride; 4-Bromo-DL-phenylglycinonitrile hydrochloride; p-Bromophenylglycinonitrile hydrochloride; α-Amino-p-bromobenzeneacetonitrile hydrochloride; (4-Bromobenzyl)cyanamide hydrochloride
EINECS	Contact for details

Quality Control

Our Benzeneacetonitrile, α-Amino-4-Bromo-, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.