Description

3-(Acetylamino)-5-(2-Amino-2-Oxoethyl)-2,4,6-Triiodobenzoic Acid is a high-purity, tri-iodinated organic compound primarily used as a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its precise molecular structure, which is essential for producing high-contrast, non-ionic X-ray contrast media agents. It is specifically needed by manufacturers in the pharmaceutical and fine chemical industries engaged in the research, development, and production of diagnostic imaging agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of non-ionic, low-osmolar X-ray contrast media such as Iopamidol and Ioversol.
• Diagnostic Imaging Agent Synthesis: Used in the production of iodinated compounds for computed tomography (CT) scans, angiography, and myelography.
• Research & Development: Serves as a crucial reference standard and starting material in medicinal chemistry research for novel contrast agents.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized, high-value iodinated aromatic compounds.

Basic Information

Product Name	3-(Acetylamino)-5-(2-Amino-2-Oxoethyl)-2,4,6-Triiodobenzoic Acid
CAS No.	40590-65-6
Molecular Formula	C11H9I3N2O4
Molecular Weight	645.91 g/mol
Synonyms	5-Acetamido-2,4,6-triiodo-N-(carbamoylmethyl)isophthalamic Acid; Iopamidol Intermediate; Ioversol Intermediate; 5-Acetamido-2,4,6-triiodoisophthalamic Acid N-(Carbamoylmethyl) Amide; 2,4,6-Triiodo-5-[(2-oxo-2-aminoethyl)carbamoyl]-N-acetylaniline; 40590-65-6; Triiodinated Benzoic Acid Derivative
EINECS	Contact for details

Quality Control

Our 3-(Acetylamino)-5-(2-Amino-2-Oxoethyl)-2,4,6-Triiodobenzoic Acid is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.