Description

5-Bromo-2-Hydroxybenzonitrile is a versatile halogenated aromatic nitrile compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a phenolic hydroxyl group, makes it a valuable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its rigid, substituted benzene core.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and scaled-up processes.

Basic Information

Item	Details
Product Name	5-Bromo-2-Hydroxybenzonitrile
CAS No.	40530-18-5
Molecular Formula	C7H4BrNO
Molecular Weight	198.02 g/mol
Synonyms	2-Hydroxy-5-bromobenzonitrile; 5-Bromo-2-cyanophenol; 5-Bromosalicylonitrile; 2-Cyano-4-bromophenol; 4-Bromo-2-hydroxybenzonitrile; 5-Bromosalicylonitrile; 5-Bromo-2-hydroxybenzonitrile; 5-Bromo-2-cyanophenol
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Hydroxybenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.