Description

(Rs)-Boc-2-(3-Methyl-Phenyl)Glycine is a protected amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a crucial chiral building block for the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, including enzyme inhibitors and receptor modulators.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a non-natural, substituted phenylglycine residue into peptide chains.
• Proteomics Research: Employed in the design and synthesis of peptide-based probes and tools for studying protein-protein interactions and biological pathways.
• Agrochemical Development: Serves as a building block for creating chiral active ingredients in crop protection products.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to create enantiomerically enriched compounds.
• Chemical Biology: Incorporated into molecular scaffolds for drug discovery and the development of bioactive compounds.

Basic Information

Product Name	(Rs)-Boc-2-(3-Methyl-Phenyl)Glycine
CAS No.	40512-50-3
Molecular Formula	C₁₄H₁₉NO₄
Molecular Weight	265.31 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-3-methyl-DL-phenylglycine; Boc-3-methyl-DL-phenylglycine; (RS)-2-[(tert-Butoxycarbonyl)amino]-2-(3-methylphenyl)acetic acid; (R,S)-Boc-m-Tolylglycine; DL-N-Boc-3-methylphenylglycine; tert-Butyl (RS)-(3-methylphenyl)(carboxymethyl)carbamate; 2-[(tert-Butoxycarbonyl)amino]-2-(3-methylphenyl)acetic acid (racemic)
EINECS	Contact for details

Quality Control

Our (Rs)-Boc-2-(3-Methyl-Phenyl)Glycine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Racemic mixture (RS ~50:50)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.