Description

4-Trifluoromethylbenzylmethylsulfone is a versatile organosulfur compound featuring a trifluoromethylphenyl group, making it a valuable fluorinated building block. This compound is critical for introducing specific electronic and steric properties into target molecules, enhancing their biological activity and material characteristics. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for use in synthesis and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to incorporate sulfone and fluorinated aromatic moieties into specialty polymers, enhancing thermal stability and chemical resistance.
• Cross-Coupling Reactions: Acts as a substrate or reagent in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex biaryl systems.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D for exploring new fluorination methodologies and reaction pathways.

Basic Information

Product Name	4-Trifluoromethylbenzylmethylsulfone
CAS No.	40289-23-4
Molecular Formula	C9H9F3O2S
Molecular Weight	238.23 g/mol
Synonyms	1-[(4-Trifluoromethyl)phenyl]-1-methanesulfonylethane; (4-(Trifluoromethyl)phenyl)methyl methyl sulfone; α-Tolyl methyl sulfone, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)benzyl Methyl Sulfone; 4-(Trifluoromethyl)phenylmethylsulfonylmethane; Methyl (4-trifluoromethylbenzyl) sulfone; p-Trifluoromethylbenzylmethylsulfone
EINECS	Contact for details

Quality Control

Our 4-Trifluoromethylbenzylmethylsulfone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.