Description

3'-Fluoro-2-Phenylacetophenone is a high-purity fluorinated aromatic ketone building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers and liquid crystals with unique optical and electronic properties.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of fluorinated electron-transport materials and emissive layer components.
• Academic & Industrial R&D: A versatile reagent for methodological studies in cross-coupling reactions and fluorine chemistry.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other performance chemicals requiring specific fluorinated aromatic structures.

Basic Information

Product Name	3'-Fluoro-2-Phenylacetophenone
CAS No.	40281-50-3
Molecular Formula	C14H11FO
Molecular Weight	214.24 g/mol
Synonyms	2-Acetyl-3'-fluorobiphenyl; 1-(3-Fluoro[1,1'-biphenyl]-2-yl)ethanone; 3'-Fluoro-2-phenylacetophenone; 3-Fluorobiphenyl-2-yl methyl ketone; 2-Acetyl-3-fluorobiphenyl; 2-(3-Fluorophenyl)acetophenone; Ethanone, 1-[1,1'-biphenyl]-3-fluoro-2-yl-; 3'-Fluoro-2-acetylbiphenyl
EINECS	Contact for details

Quality Control

Our 3'-Fluoro-2-Phenylacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.